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Partner Institute for Computational Biology (PICB) Workshop

The Organization and Control of Metabolic Networks

4-6 August, 2007, Shanghai Institutes for Biological Sciences, CAS

organizers: Andreas Dress, Terence Hwa, Luhua Lai, Yixue Li, Leihan Tang

Preliminary Program

Note: * indicates session discussion leader
 

Saturday, 4 August

Afternoon
3:30 – 7:30 pm  Registration, PICB Room 315 
4:30 – 5:30 pm  Room 300: Tutorial on metabolism from a physicist’s viewpoint Eric Smith, Santa Fe Institute  
5:30 – 7:00 pm  Welcome dinner, Hong Yun-lou restaurant, 567 Zhaojiabang Rd 

Evening
7:30 – 10:00 pm Introduction and Overview
From molecules to physiology: some basic concepts and issues Terry Hwa*(华泰立), University of California, San Diego

Systems biology: metabolic networks and metabolomics Xue-Ming Zhao(赵学明), Tianjin University

From gut microbiota to host global metabolism – a top-down systems perspectiveLi-Ping Zhao(赵立平), Shanghai Jiaotong University
Sunday, 5 August

Morning
8:30 – 10:30 am  Metabolic Regulation and Control: Case Studies

Dynamics and design features of a basic regulatory architecture controlling metabolic pathways Hao Li*(李浩), University of California, San Francisco

Strain improvement by metabolic engineering: riboflavin production as a case study for systems biology Xue-Ming Zhao*(赵学明), Tianjin University

Towards the production of polyhydroxyalkanoates in recombinant E.coli Qing-Sheng Qi(祁庆生), Shandong University  
Break
10:45 – 12:15 pm  Computational and Theoretical Studies of Metabolism I

The expanded flux variability analysis on metabolic network of E. coli Qi Ouyang(欧阳颀), Peking University

Metabolic network simplification for quantitative systems level analysis Lei-Han Tang*(汤雷翰), Hong Kong Baptist University

The arachidonic acid metabolic network: flux balance, control, and implications for network based drug design. Lu-Hua Lai(来鲁华), Peking University

Lunch

Afternoon
2:00 – 4:00 pm Metabolic Profiling: Mass Spec and NMR

An example of using LC-MS for metabonomics study Zong-Wei Cai*(蔡宗苇), Hong Kong Baptist University

Metabolic profiling as a systems pharmacological tool Wei Jia(贾伟), Shanghai Jiaotong University

Seeking non-biased and holistic in vivo metabonomics tools ---Back to Basics Hui-Ru Tang(唐惠儒), Wuhan Institute of Physics and Mathematics

Break
4:15 – 5:45 pm Computational and Theoretical Studies of Metabolism II

What information can be gained from a network's topology, only? Andreas Dress*, Max-Planck Institute, Shanghai

Topological structure of metabolic pathway networks Yi-Xue Li(李亦学), Shanghai Center for Bioinformatics Technology

Control-first or Metabolism-first in the origin of life? Eric Smith, Santa Fe Institute

 
Evening
6:00 – 8:00 pm  Conference dinner,Nanling Resturant , 168 Yue Yang Road, By Yongjia Road
after dinner  Informal discussions on collaborative and funding opportunities 

Monday, 6 August

Morning
8:30 – 10:30 am  Metabolism and Cellular Biology: Stress Response etc.

The regulation of the unfolded protein response Nai-Sum Wong, University of Hong Kong

Role of hypoxia inducible factor (HIF) in aerobic and anaerobic respiration Chen Zeng*(曾辰), George Washington University

 
Break
10:45 – 12:15  Roundtable Discussion on Future Directions
Facilitators:
Chao Tang(汤超), University of California, San Francisco
Jia-Rui Wu(吴家睿), Shanghai Institute of Biological Science, CAS
Li-Ping Zhao(赵立平), Shanghai Jiaotong University
 
12:30pm  Adjourning lunch 


320 Yue Yang Road,Shanghai, China, Fax:86-21-54920451,Email:icb@sibs.ac.cn