MPG-CAS Partner Institute for Computational Biology (PICB),

Shanghai Institute of Biological Sciences, 320 Yueyang Road, Shanghai 200031, P. R. China

 
And finally: PHOTOS!

Objective || Topics & Teachers || Schedule || NEW! Course material NEW!  || For speakers || For participants || Contact || PICB home

Objective

Proteins are engines of life, enabling living organisms to move, metabolize and sense, in short, to function. To fulfill such diverse tasks, proteins take up a specific fold, i.e. a position in a complex high-dimensional free energy landscape, with narrow valleys or vast plateaus, from which they wander around. What are the underlying principles of protein walking tours - of protein folds, (un)folding, and functioning?

This EMBO-course gives insight into the current state of structural proteomics, molecular simulations, and energy calculations to address this question. It aims at young Chinese and European scientists working in the field of theoretical and computational protein science. This EMBO course intends to emphasize general concepts and theoretical methods, their strengths and pitfalls. Apart from the methods and techniques taught in the practical courses, the participants shall learn how to address their question by means of appropriate simulations, and how to properly draw meaningful conclusions.
The "MPG/CAS Partner Institute for Computational Biology" (PICB) is the first Max-Planck Partner Institute in China. It has opened its doors on Oct 1, 2005. It aims at the development and application of theoretical methods in molecular biology for analyzing the complex processes and networks in living systems. The new research institute will complement research activities at the MPG and the CAS through main components in theoretical biology carried out in three departments and several Junior Research Groups.

Up

Topics & Teachers

Protein free energy landscapes

  • Free energy landscapes of (un)folded protein ensembles
  • Energetics and kinetics of folding
  • Simulating/predicting protein aggregation

    Structural Genomics/Proteomics

  • Protein structure prediction
  • Functional residues and sites in sequences and structures
  • Protein-protein/protein-ligand binding prediction

    Enforced protein unfolding/unbinding

  • Non-equilibrium protein dynamics
  • Probing protein energy landscapes by force

    Teachers

    Protein free energy landscapese

  • Vijay Pande, Stanford (confirmed)
  • Michele Vendrusculo, University of Cambridge (confirmed)
  • Amedeo Caflisch, University of Zürich (confirmed)
  • Hualiang Jiang, Shanghai Institute of Materia Medica (confirmed)
  • Haiyan Liu, University of Science and Technology, Hefei (confirmed)
  • Michael Nilges, Institut Pasteur, Paris (confirmed)
  • Hue Sun Chan, University of Toronto (confirmed)

    Structural Genomics/Proteomics

  • William R. Atchley, North Carolina State University, Raleigh (confirmed)
  • Rama Ranganathan, University of Texas, Dallas (confirmed)

    Enforced protein unfolding/unbinding

  • Jane Clarke, University of Cambridge (confirmed)
  • Helmut Grubmüller, MPI for Biophysical Chemistry, Göttingen (confirmed)

    Up

    Schedule

    embo06_schedule.pdf


    Course site:

    Shanghai Institute of Advanced Sciences
    No. 11 Building,
    319 Yueyang Road
    www.sias.ac.cn

    For directions see:
    www.sias.ac.cn/p2.html

    Up

    Course material & Links

    available upon request

    Up

    For speakers

  • Accomodation will be arranged for the duration of your stay at:

    Hope Hotel***

    500 Zhao Jia Bang Road, Shanghai 200031, China
    Tel: 64716060, Fax: 64710089
    www.hope-hotel.com

    5 min walking distance to the EMBO course site

  • You will be picked up at the Shanghai Pudong International Airport - please watch out for a sign "EMBO 2006" after exiting the baggage claim area.

  • Sightseeing programmes can be arranged individually, please contact us prior or during the course, if you are interested.

    Up

    For participants

  • Accomodation will be arranged for the duration of your stay if you wish so

    Guest house of the Chinese Academy of Sciences
     319 Yue Yang Road, Shanghai 200031, China

    The guest house is located opposite of the EMBO course site

  • Check-in:

    Tue, May 9th, 5-7pm or Wed, May 10th, 9-10am Shanghai Institute of Advanced Sciences
    No. 11 Building,
    319 Yueyang Road
    www.sias.ac.cn
  • There is no registration fee for course participants. The costs of student accommodation and subsistence is covered by the EMBO.
  • For further questions please contact

    Dr. Yechun Xu

    yechun.xu[at]weizmann.ac.il
    Department of Stuctural Biology
    Weizmann Institute of Science
    Rehovot 76100, Israel
    Tel: +972 8 934 2397
    Fax: +972 8 934 4159


    Up

    Contact

    Frauke Gräter

    Tel: +49551 2012320
    frauke.graeter[at]mpi-bpc.mpg.de
    Max-Planck-Institute for Biophysical Chemistry
    Am Fassberg 11, 37077 Göttingen, Germany

    Prof. Andreas Dress

    Tel: +86 21 50806600*1210
    dress[at]sibs.ac.cn
    MPG-CAS Partner Institute for Computational Biology (PICB)
    320 Yueyang Road, Shanghai 200031, P. R. China

    Up