Proteins are
exposed to and tightly regulated by external perturbations, binding
partners and mechanical stress, altering their assembly and reactivity.
Revealing the molecular driving forces and evolutionary constraints in
biomolecular systems is a requirement of designing biological materials
and processes, for applications in material science and biomedicine,
which is the aim of our research. Our research focuses on protein
materials and fibers such as silk, disordered proteins and protein
folding, the extra-cellular matrix, enzymes and allosteric proteins.
Evolutionary design is a complementary aspect we consider for
understanding physiological functions of these systems. We make use and
further develop various computational and theoretical techniques, among
others molecular modelling, high-performance molecular simulations,
finite element analysis and bioinformatics approaches. For virtually
all of the projects, we extensively collaborate with experimental
research labs.
This junior
research group led by Frauke Gräter has been established in July 2007,
funded by the Max Planck Society. We recently moved to the EML Research gGmbH in
Heidelberg.
And here we are:
News
We moved!
We are now working at the EML
Research gGmbH in Heidelberg, while remaining co-affiliated with
the PICB in Shanghai. Come visit our group 'Molecular Biomechanics'
(MBM) soon there!
