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Selected Publications

1. Zongyang Lu, Jie Li, Yong Lu, Ling Li, Wei Wang, Chenchen Zhang, Libing Xu, Yanhong Nie, Changshan Gao, Xinyan Bian, Zhen Liu*, Guang-Zhong Wang*, Qiang Sun*. Cynomolgus-rhesus hybrid macaques serve as a platform for imprinting studies, The Innovation, 2023; 4(3):100436.

2. Wei Wang, Tingting Bo, Ge Zhang, Jie Li, Junjie Ma, Liangxiao Ma, Ganlu Hu, Huige Tong, Qian Lv, Daniel J. Araujo, Dong Luo, Yuejun Chen, Meiyun Wang, Zheng Wang* and Guang-Zhong Wang*. Noncoding transcripts are linked to brain resting-state activity in non-human primates, Cell Reports, 2023; 42(6):112652.

3. Yuhao Chi, Ruicheng Qi, Yue Zhou, Huige Tong, Hanbo Jin, Christoph W Turck, Wei-Hua Chen, Guang-Zhong Wang*. scBrainMap: a landscape for cell types and associated genetic markers in the brain, Database, 2023;2023:baad035.

4. Tingting Bo, Jie Li, Ganlu Hu, Ge Zhang, Wei Wang, Qian Lv, Shaoling Zhao, Junjie Ma, Meng Qin, Xiaohui Yao, Meiyun Wang, Guang-Zhong Wang*, Zheng Wang*. Brain-wide and cell-specific transcriptomic insights into MRI-derived cortical morphology in macaque monkeys. Nat Commun. 2023;14(1):1499.

5. Jie Li, Pengxing Nie, Christoph W Turck, Guang-Zhong Wang*. Gene networks under circadian control exhibit diurnal organization in primate organs. Commun Biol. 2022;5(1):76

6. Wenqian Zhang, Wei Wang, Manman Zhao, Christoph W Turck, Ying Zhu, Guang-Zhong Wang*. Rapid Body-Wide Transcriptomic Turnover During Rhesus Macaque Perinatal Development. Front Physiol. 12. 2021;12:690540.

7. Ganlu Hu, Jie Li, Guang-Zhong Wang*. Significant Evolutionary Constraints on Neuron Cells Revealed by Single-Cell Transcriptomics. Genome Biol Evol. 2020;12(4):300-308.

8. Wei Wang, Guang-Zhong Wang*. Twin-peak temporal regulation during human neocortical development. Cell Discov. 2019;5:61.

9. Yang Cheng, Yuhao Chi, Luoying Zhang, Guang-Zhong Wang*. A single factor dominates the behavior of rhythmic genes in mouse organs. BMC Genomics 2019;20(1):879.

10.Stefano Berto#, Guang-Zhong Wang#, James Germi, Bradley C Lega, Genevieve Konopka. Human Genomic Signatures of Brain Oscillations During Memory Encoding. Cereb Cortex 2018;28(5):1733-1748.

11. Simone Marini*, Nelson Nazzicari, Filippo Biscarini, Guang-Zhong Wang*. Dscam1 web server: online prediction of Dscam1 self- and hetero-affinity. Bioinformatics 2017;33(12):1879-1880.

12. Guang-Zhong Wang, Stephanie L Hickey, Lei Shi, Hung-Chung Huang, Prachi Nakashe, Nobuya Koike, Benjamin P Tu, Joseph S Takahashi, Genevieve Konopka. Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale. Cell Rep. 2015;13(9):1868-1880.

13. Guang-Zhong Wang#, T Grant Belgard#, Deng Mao, Leslie Chen, Stefano Berto, Todd M Preuss, Hanzhang Lu, Daniel H Geschwind, Genevieve Konopka. Correspondence between Resting-State Activity and Brain Gene Expression. Neuron 2015;88(4):659-666.

All Publications

5. Jie Li, Pengxing Nie, Christoph W Turck, Guang-Zhong Wang*. Gene networks under circadian control exhibit diurnal organization in primate organs. Commun Biol. 2022;5(1):76

7. Luoying Zhang, Christoph W Turck, Guang-Zhong Wang*. Editorial: Time, genetics, and complex disease. Front Genet.2022;13:1016049.

8. Shi-Yuan Tong, Ke Fan, Zai-Wei Zhou, Lin-Yun Liu, Shu-Qing Zhang, Yinghui Fu, Guang-Zhong Wang, Ying Zhu, Yong-Chun Yu. mvPPT: A highly efficient and sensitive pathogenicity prediction tool for missense variants.Genomics Proteomics Bioinformatics 2022;S1672-0229(22).

9. Jie Li, Pengxing Nie, Christoph W Turck, Guang-Zhong Wang*. Gene networks under circadian control exhibit diurnal organization in primate organs. Commun Biol. 2022;5(1):764.

10. Kazuya Toriumi, Guang-Zhong Wang, Stefano Berto, Noriyoshi Usui. Editorial: Decoding Brain Function Through Genetics. Front Genet. 2022;13:874350.

11. Xueru Zhu, Yiting Wang, Chang Jiang, Xiaoyang Li, Linying Sun, Guang-Zhong Wang, Xiaolong Fu. Radiosensitivity-Specific Proteomic and Signaling Pathway Network of Non-Small Cell Lung Cancer (NSCLC). Int J Radiat Oncol Biol Phys. 2022;112(2):529-541.

12. Wenqian Zhang, Wei Wang, Manman Zhao, Christoph W Turck, Ying Zhu, Guang-Zhong Wang*. Rapid Body-Wide Transcriptomic Turnover During Rhesus Macaque Perinatal Development. Front Physiol. 12. 2021;12:690540.

13. Linhua Gan, Jingjing Sun, Shuo Yang, Xiaocui Zhang, Wu Chen, Yiyu Sun, Xiaohua Wu, Cheng Cheng, Jing Yuan, Anan Li, Mark A Corbett, Mathew P Dixon, Tim Thomas, Anne K Voss, Jozef Gécz, Guang-Zhong Wang, Azad Bonni, Qian Li, Ju Huang. Chromatin-Binding Protein PHF6 Regulates Activity-Dependent Transcriptional Networks to Promote Hunger Response. Cell Rep. 2020;30(11):3717-3728.

14. Dan-Chao Cai, Zhiwei Wang, Tingting Bo, Shengyao Yan, Yilin Liu, Zhaowen Liu, Kristina Zeljic, Xiaoyu Chen, Yafeng Zhan, Xiu Xu, Yasong Du, Yingwei Wang, Jing Cang, Guang-Zhong Wang, Jie Zhang, Qiang Sun, Zilong Qiu, Shengjin Ge, Zheng Ye, Zheng Wang. MECP2 Duplication Causes Aberrant GABA Pathways, Circuits and Behaviors in Transgenic Monkeys: Neural Mappings to Patients with Autism. J Neurosci. 2020;40(19):3799-3814.

15. Yan Li, Yongli Shan, Gokhul Krishna Kilaru, Stefano Berto, Guang-Zhong Wang, Kimberly H Cox, Seung-Hee Yoo, Shuzhang Yang, Genevieve Konopka, Joseph S Takahashi. Epigenetic inheritance of circadian period in clonal cells. Elife 2020; 9:e54286.

16. Ganlu Hu, Jie Li, Guang-Zhong Wang*. Significant Evolutionary Constraints on Neuron Cells Revealed by Single-Cell Transcriptomics. Genome Biol Evol. 2020;12(4):300-308.

17. Linying Sun, Junjie Ma, Christoph W Turck, Pin Xu, Guang-Zhong Wang*. Genome-wide circadian regulation: A unique system for computational biology. Comput Struct Biotechnol J. 2020;18:1914-1924.

18. Wei Wang, Guang-Zhong Wang,*. Understanding Molecular Mechanisms of the Brain Through Transcriptomics. Front Physiol. 2019;10:214.

19. Liqiao Hu, Hao Huang, Mohan Hei, Yang Yang, Sheng Li, Yunshan Liu, Zhen Dou, Mengying Wu, Jie Li, Guang-Zhong Wang, Xuebiao Yao, Hong Liu, Xiaojing He, Wei Tian. Structural analysis of fungal CENP-H/I/K homologs reveals a conserved assembly mechanism underlying proper chromosome alignment. Nucleic Acids Res. 2019;47(1):468-479.

20. Jie Li, Guang-Zhong Wang*. Application of Computational Biology to Decode Brain Transcriptomes. Genomics Proteomics Bioinformatics 2019;17(4):367-380.

21. Yang Cheng, Yuhao Chi, Luoying Zhang, Guang-Zhong Wang*. A single factor dominates the behavior of rhythmic genes in mouse organs. BMC Genomics. 2019;20(1):879.

22. Wei Wang, Guang-Zhong Wang*. Twin-peak temporal regulation during human neocortical development. Cell Discov. 2019;5:61.

23. Stefano Berto#, Guang-Zhong Wang#, Germi J, Lega BC, Konopka G. Human Genomic Signatures of Brain Oscillations During Memory Encoding. Cereb Cortex 2018;28(5):1733-1748.

24. Ganlu Hu, Guang-Zhong Wang*. Decoding nervous system by single-cell RNA sequencing[J]. Quantitative Biology 2017, 5(3): 210-214.

25. Simone Marini*, Nelson Nazzicari, Filippo Biscarini, Guang-Zhong Wang*. Dscam1 web server: online prediction of Dscam1 self- and hetero-affinity. Bioinformatics 2017;33(12):1879-1880.

26. Guang-Zhong Wang, Stephanie L. Hickey, Lei Shi, Hung-Chung Huang, Prachi Nakashe, Nobuya Koike, Benjamin P. Tu, Joseph S. Takahashi, Genevieve Konopka. Cycling Transcriptional Networks Optimize Energy Utilization on a Genome Scale. Cell Rep. 2015;13(9):1868-1880.

27. Guang-Zhong Wang#, T. Grant Belgard#, Deng Mao, Leslie Chen, Stefano Berto, Todd M. Preuss, Hanzhang Lu, Daniel H. Geschwind, Genevieve Konopka,. Correspondence between Resting-State Activity and Brain Gene Expression. Neuron 2015;88(4):659-666.

28. Guang-Zhong Wang#, Simone Marini#, Xinyun Ma, Qiang Yang, Xuegong Zhang, Yan Zhu. Improvement of Dscam homophilic binding affinity throughout Drosophila evolution. BMC Evol Biol. 2014;14:186.

29. Guang-Zhong Wang, Genevieve Konopka*. Decoding human gene expression signatures in the brain. Transcription 2013;4(3):102-108.

30. Genevieve Konopka, Tara Friedrich, Jeremy Davis-Turak, Kellen Winden, Michael C. Oldham, Fuying Gao, Leslie Chen, Guang-Zhong Wang, Rui Luo, Todd M. Preuss, Daniel H. Geschwind. Human-Specific Transcriptional Networks in the Brain, Human-specific transcriptional networks in the brain. Neuron 2012;75(4):601-617.

31. Guang-Zhong Wang, Genevieve Konopka. Differential functional constraints on the evolution of postsynaptic density proteins in neocortical laminae. PLoS One 2012;7(6):e39686.

32. Guang-Zhong Wang, Martin J Lercher, Laurence D Hurst. Transcriptional coupling of neighboring genes and gene expression noise: evidence that gene orientation and noncoding transcripts are modulators of noise. Genome Biol Evol. 2011;3:320-331.

33. Guang-Zhong Wang, Jian Liu, Wei Wang, Hong-Yu Zhang, Martin J Lercher. A gene's ability to buffer variation is predicted by its fitness contribution and genetic interactions. PLoS One 2011;6(3):e17650.

34. Guang-Zhong Wang, Martin J Lercher. The effects of network neighbours on protein evolution. PLoS One 2011;6(4):e18288.

35. Liang-Yu Fu, Guang-Zhong Wang, Bin-Guang Ma, Hong-Yu Zhang. Exploring the common molecular basis for the universal DNA mutation bias: revival of Löwdin mutation model. Biochem Biophys Res Commun. 2011;409(3):367-371.

36. Guang-Zhong Wang, Wei-Hua Chen, Martin J Lercher. Coexpression of linked gene pairs persists long after their separation. Genome Biol Evol. 2011;3:565-570.

37. Guang-Zhong Wang, Martin J Lercher. Amino acid composition in endothermic vertebrates is biased in the same direction as in thermophilic prokaryotes. BMC Evol Biol. 2010;10:263.

38. Tobias Warnecke, Guang-Zhong Wang, Martin J Lercher, Laurence D Hurst. Does negative auto-regulation increase gene duplicability? BMC Evol Biol. 2009;9:193.

39. Ling-Ling Chen, Guang-Zhong Wang, Hong-Yu Zhang. Sterol biosynthesis and prokaryotes-to-eukaryotes evolution. Biochem Biophys Res Commun. 2007;363(4):885-888.

40. Guang-Zhong Wang, Ling-Ling Chen, Hong-Yu Zhang. Phase-dependent nucleotide substitution in protein-coding sequences. Biochem Biophys Res Commun. 2007;355(3):599-602.

41. Guang-Zhong Wang, Ling-Ling Chen, Hong-Yu Zhang. Neighboring-site effects of amino acid mutation. Biochem Biophys Res Commun. 2007;353(3):531-534.

42. Guang-Zhong Wang#, Bin-Guang Ma#, Yan Yang, Hong-Yu Zhang. Unexpected amino acid composition of modern Reptilia and its implications in molecular mechanisms of dinosaur extinction. Biochem Biophys Res Commun. 2005;333(4):1047-1049.