population genomics | Welcome to PGG

Welcome to PGG Welcome to PGG. PGG is affiliated with PICB – Chinese Academy of Sciences (CAS) and German Max Planck Society (MPG) partner institute for computational biology. The goal of the Population Genomics Group (PGG) is to understand the evolutionary dynamics of genomes at population level using computational approaches, and to bridge evolutionary history and genomic medicine. Currently, PGG is focusing on analysis of genetic structure, inference of human...

Group Meeting 13/01/20

Speaker: CHEN Hao Time: 13:00 – 14:00, Jan 13, 2020 Venue: Room 315, SIBS Main Building Title: Paternal and maternal lineages in Asia inferred from next-generation sequencing data Speaker: ZHANG Rui Time: 14:00 – 15:00, Jan 13, 2020 Venue: Room 315, SIBS Main Building Title: Human demographic history inference based on genome wide recombination and local ancestry information Speaker: XIE Bo Time: 15:00 – 16:00, Jan 13,...

Group Meeting 06/01/20

Speaker: WANG Yimin Time: 13:00 – 14:00, Jan 06, 2020 Venue: Room 315, SIBS Main Building Title: Adaptive archaic introgression of copy number variants and the discovery of previously unknown human genes Abstract: Copy number variants (CNVs) are subject to stronger selective pressure than single-nucleotide variants, but their roles in archaic introgression and adaptation have not been systematically investigated. We show...

Group Meeting 30/12/19

Speaker: WANG Yinan Time: 13:00 – 14:00, Dec 30, 2019 Venue: Room 315, SIBS Main Building Title: Trans Effects on Gene Expression Can Drive Omnigenic Inheritance Abstract: Early genome-wide association studies (GWASs) led to the surprising discovery that, for typical complex traits, most of the heritability is due to huge numbers of common variants with tiny effect sizes. Previously, we argued that new models are needed to...

Group Meeting 23/12/19

Speaker: PAN Yuwen Time: 13:00 – 14:00, Dec 23, 2019 Venue: Room 315, SIBS Main Building Title: Evaluation of the RALATE software Speaker: WANG Yimin Time: 14:00 – 15:00, Dec 23, 2019 Venue: Room 315, SIBS Main Building Title: Structural variation in the sequencing...

Group Meeting 16/12/19

Speaker: LOU Haiyi Time: 13:00 – 14:00, Dec 16, 2019 Venue: Room 315, SIBS Main Building Title: An open resource of structural variation for medical and population genetics Abstract: Structural variants (SVs) rearrange large segments of the genome and can have profound consequences for evolution and human diseases. As national biobanks, disease association studies, and clinical genetic testing grow increasingly reliant on...

Group Meeting 09/12/19

Speaker: LIU Jiaojiao Time: 13:00 – 14:00, Dec 09, 2019 Venue: Room 315, SIBS Main Building Title: The GenomeAsia 100K Project enables genetic discoveries across Asia Abstract: The underrepresentation of non-Europeans in human genetic studies so far has limited the diversity of individuals in genomic datasets and led to reduced medical relevance for a large proportion of the world’s population. Population-specific...

Group Meeting 02/12/19

Speaker: GE Xueling Time: 13:00 – 14:00, Dec 02, 2019 Venue: Room 315, SIBS Main Building Title: Genomics of disease risk in globally diverse populations Abstract: Risk of disease is multifactorial and can be shaped by socio-economic, demographic, cultural, environmental and genetic factors. Our understanding of the genetic determinants of disease risk has greatly advanced with the advent of genome-wide association studies...

Group Meeting 25/11/19

Speaker: HUANG Ke Time: 13:00 – 14:00, Nov 25, 2019 Venue: Room 315, SIBS Main Building Title: The impact of short tandem repeat variation on gene expression Abstract: Short tandem repeats (STRs) have been implicated in a variety of complex traits in humans. However, genome-wide studies of the effects of STRs on gene expression thus far have had limited power to detect associations and provide insights into putative...

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