Principal Investigator
Andrew E Teschendorff
From: University College London
Room: 332
Tel:
Email: a.teschendorff@ucl.ac.uk
Date of Arrival: 2013-09-09
Research Area:
Cancer System-omics
/ Statistical Cancer Genomics
/ Epigenomics
/ Network Physics
In our lab we are developing and applying novel advanced statistical methods, drawn from diverse areas such as graph theory, network physics, machine learning and signal processing, to help tackle some of the outstanding challenges in cancer genomics and epigenomics.
We are particularly interested in using the language of networks and statistical mechanics to help elucidate the systems biology principles underlying normal cellular differentiation and how this process is altered in complex diseases such as cancer. We are developing a framework based on statistical mechanics and network theory, in order to help identify the key signaling pathways and nodes in differentiation, cancer and drug resistance.
Another application of networks and graph theory is to the integrative analysis of large-scale multi-dimensional omic data sets. For instance, we have recently used interactome and regulatory networks to integrate epigenetic and gene expression data together, to identify functional epigenetic drivers in cancer and ageing. We are continuing to explore and develop such "Systems Epigenomics" approaches.
We are also involved in numerous more data-driven projects, in close collaboration with clinicians and biologists. One key area of interest is in cancer risk prediction and early detection: we are involved in the analysis of DNA methylation data from large prospective studies in order to assess if DNA methylation marks measured years in advance of disease diagnosis can predict the risk of disease. Another area of interest is in refining the molecular taxonomy of cancers, using perturbation molecular signature approaches to identify novel prognostic and predictive cancer subtypes.
Post Doc one
Alok Kumar Maity
From: University of Calcutta
Room: 301
Tel: +8618621356748
Email: alok@picb.ac.cn
Date of Arrival: 2019-11-25
Role: Post Doc
PhD. Students Four
Han Jing
From: Shandong University
Room: 301
Tel: +8618516339336
Email: jinghan@picb.ac.cn
Date of Arrival: 2016-09-01
Tianyu Zhu
From: Fudan University
Room: 301
Tel: +8615121161258
Email: zhutianyu@picb.ac.cn
Date of Arrival: 2018-09-01
Chenglong You
From:Huazhong Agriculture University
Room: 328
Tel:
Email: clyou@sibs.ac.cn
Date of Arrival: 2018-09-20
Qi Luo
From: Nanjing University
Room: 301
Tel: +8613270898933
Email: luoqi@picb.ac.cn
Date of Arrival: 2019-09-01
Master Student one
Xue Hu
From: Tianjin Medical University
Room: 328
Tel: +8618516682617
Email: huxue2018@sibs.ac.cn
Date of Arrival: 2018-09-01
Role: Student
Staff one
Kangying Wang
From: Shanghai University
Room: 301
Tel: +86 13916008523
Email: wangkangying@picb.ac.cn
Date of Arrival: 2019-09-09
Role: Research assistant
Alumni Fifteen
Yinming Jiao
From: Zhejiang University
Email: 20907099@zju.edu.cn
Date of Arrival: 2014-01-13
Role: Research Assistant
Linlin Li
From: UCL
Email: 165680699@qq.com
Date of Arrival: 2014-02-13
Role: Research Assistant
Yiru Shen
From: Shanghai Jiao Tong University
Email: shenyiru@picb.ac.cn
Date of Arrival: 2015-09-7
Role: Research Assistant
Yuting Chen
From: Sichuan Agricutural University
Email: chenyuting@picb.ac.cn
Date of Arrival: 2013-09-01
Role: Ph.D
Yang Gao
From: Liaoning Normal University
Email: gaoyang0218@gmail.com
Date of Arrival: 2013-03-04
Role: Ph.D
Yuan Tian
From: Harbin Institute of Technology
Email: tianyuan1991hit@gmail.com
Date of Arrival: 2013-09-02
Role: Ph.D
Rui Cui
From: Shanghai Institutes for Biological Sciences
Email: cuirui@picb.ac.cn
Date of Arrival: 2017-08-01
Role: Research Assistant
Meng Li
From: Harbin Engineering University
Email: limeng@picb.ac.cn
Date of Arrival: 2017-11-29
Role: Research Assistant
Shoufeng Huang
From: Heilongjiang University
Email: huangshoufeng@picb.ac.cn
Date of Arrival: 2018-09-10
Role: Research Assistant
Shijie C. Zheng
From: Xiamen University
Email: shijieczheng@gmail.com
Date of Arrival: 2014-02-18
Role: Ph.D
Danyue Dong
From: Nanjing Agricutural University
Tel: +8617602182662
Email: dongdanyue@picb.ac.cn
Date of Arrival: 2016-09-01
Role: Student
Rong Gao
From: The University of Sydney
Tel: +86 15821479207
Email: gaorong@picb.ac.cn
Date of Arrival: 2019-04-01
Role: Staff Scientist
Weiyan Chen
From: Ocean University of China
Tel: +8615102169675
Email: chenweiyan@picb.ac.cn
Date of Arrival: 2017-09-01
Role: Student
Ning Wang
From: Shandong Agriculture University
Tel:
Email: wangning@picb.ac.cn
Date of Arrival: 2017-09-01
Role: Student
Md Wahiduzzaman
From: Bangabandhu Sheikh Mujibur Rahman Science and Technology University
Tel: +8613621227212
Email: wahid@picb.ac.cn
Date of Arrival: 2020-01-13
Role: Student